姓名：聂晶
职称：副教授
专业：有机化学
单位：化学系
电话： 022-27403475
EMAIL： niejing1121@126.com
研究方向1：有机氟化学
研究方向2：不对称合成
研究简历：
2004/09～2009/07：天津大学理学院，博士，导师：马军安教授
2009/07～2012/12：天津大学理学院，讲师
2012/12～至今：天津大学理学院，副教授
代表性论文与著作：
[1] Zhang Ke-Feng,NieJing, Guo Ran, Zheng Yan, Ma Jun-An*, Chiral Phosphoric Acid-Catalyzed Asymmetric Aza-Friedel-Crafts Reaction of Indoles with Cyclic N-Acylketimines: Enantioselective Synthesis of Trifluoromethyldihydroquinazolines,Adv. Synth. Catal.355(17), 3497-3502,2013.
[2] Li Feng,NieJing, Sun Long, Zheng Yan,MaJun-An*,Silver-Mediated Cycloaddition of Alkynes with CF3CHN2: Highly Regioselective Synthesis of 3-Trifluoromethylpyrazoles,Angew. Chem., Int. Ed.52(24), 6255-6258,2013.
[3] Yuan Hai-Na, Wang Shuai,NieJing, Meng Wei, Yao Qing-Wei,MaJun-An*,Hydrogen-Bond-Directed Enantioselective Decarboxylative Mannich Reaction of -Ketoacids with Ketimines: Application to the Synthesis of Anti-HIV Drug DPC083,Angew. Chem., Int. Ed.52(14), 3869-3873,2013.
[4] Wu Jun-Wei, Li Feng, Zheng Yan,NieJing*, DABCO-mediated one-pot sequential transformation:convenient access to fluorinated 1H-pyrazol-5(4H)-ones,Tetrahedron Lett.53(36), 4828-4831,2012.
[5] Liu Cui-Bo, Meng Wei, Li Feng, Wang Shuai,NieJing, Ma Jun-An*, A Facile Parallel Synthesis of Trifluoroethyl-Substituted Alkynes,Angew. Chem., Int. Ed.51(25), 6227-6230,2012.
[6]NieJing, Hua Ming-Qing, Xiong Heng-Ying, Zheng Yan, Ma Jun-An*, Asymmetric phase-transfer-catalyzed conjugate addition of glycine imine to exocyclic alfa, beta-unsatutrated ketones: construction of polycyclic imines containing three stereocenters,J. Org. Chem.77(9), 4209-4216,2012.
[7] Li Feng,NieJing, Wu Jun-Wei, Zheng Yan, Jun-An Ma*, Stereoselective synthesis of fluorinated 2,3-dihydroquinolin-4(1H)-ones via a one-pot multistep transformation,J. Org. Chem.77(5), 2398-2406,2012.
[8] Wang Lian, Meng Wei, Zhu Chuan-Le, Zheng Yan, Nie Jing, Ma Jun-An*, The long-arm effect: influence of axially chiral phosphoramidite ligands on the diastereo- and enantioselectivity of the tandem 1,4-addition/fluorination,Angew. Chem., Int. Ed.50(40), 9442-9446,2011.
[9]NieJing, Li Xiao-Juan, Zheng Dong-Hua, Zhang Fa-Guang, Cui Shumin, Jun-An Ma*, Chiral bifunctional thiourea-catalyzed enantioselective aldol reaction of trifluoroacetaldehyde hemiacetal with aromatic ketones,J. Fluorine Chem.132(7), 468-473,2011.
[10] Zhu Chuan-Le, Zhang Fa-Guang, Meng Wei, Nie Jing, Cahard Dominique, Ma Jun-An*, Enantioselective base-free electrophilic amination of benzofuran-2(3H)-ones: catalysis by binol-derived P-spiro quaternary phosphonium salts,Angew. Chem., Int. Ed.50(26), 5869-5872,2011.
[11] Zhang Guang-Wu, Meng Wei, Ma Hai, Nie Jing, Zhang Wen-Qin, Ma Jun-An*, Catalytic enantioselective alkynylation of trifluoromethyl ketones: pronounced metal fluoride effects and implications of zinc-to-titanium transmetallation,Angew. Chem., Int. Ed.50(15), 3538-3542,2011.
[12]NieJing, Guo Hong-Chao, Cahard Dominique, Ma Jun-An*, Asymmetric construction of stereogenic carbon centers featuring a trifluomethyl group from prochiral trifluoromethylated substrates,Chem. Rev.111(2), 455-529,2011.
[13]Nie Jing,Zhang Guang-Wu, Wang Lian, Zheng Dong-Hua, Zheng Yan, Ma Jun-An*, Chiral Brønsted Acid-Catalyzed Enantioselective Arylation of Ethyl Trifluoroacetoacetate and Ethyl Trifluoropyruvate,Eur. J. Org.Chem., 3145-3149.2009
[14]NieJing, Zhang Guang-Wu, Wang Lian, Fu AiPing, Zheng Yan, Ma Jun-An*, A Perfect Double Role of CF3Groups in Activating Substrates and Stabilizing Adducts: the Chiral Brønsted Acid-Catalyzed Direct Arylation of Trifluoromethyl Ketones,Chem. Commun., 2356-2358.2009
[15]NieJing, Zhu Hong-Wei, Cui Han-Feng, Hua Ming-Qing, Ma Jun-An*, Catalytic Stereoselective Synthesis of Highly Substituted Indanones via Tandem Nazarov Cyclization and Electrophilic Flurination Trapping,Org. Lett.,9, 3053-3056.2007
主要论著：
1、《仪器分析》，刘宇主编，天津大学出版社，2010年
2、《有机化学简明教程》，郑艳主编，高等教育出版社
荣誉和奖励：
1、2011年，天津市优秀博士论文，“催化立体选择性合成含氟有机化合物的反应研究”，
2、2012年，被授予“北洋学者-青年骨干教师”称号
讲授主要课程：
1、高等有机化学
2、基础有机化学实验
3、精细合成化学实验
正在承担项目：
1、项目负责人：国家自然科学基金面上项目“仿生启发下基于β-酮酸催化脱羧反应在有机合成中的应用拓展与深入”，85万，批准号：21472137，起止时间：2015年1月～2018年12月
2、项目负责人：天津市科委青年基金项目“新型手性亲电三氟甲基化试剂的设计合成及其应用”，6万，批准号：2014FQ-0028，起止时间：2014年4月～2017年3月
已完成项目：
项目负责人：国家自然科学基金青年项目“基于潜手性三氟甲基酮及其衍生物的催化不对称转化反应研究”，19万，批准号：21002068，起止时间：2011年1月至2013年12月，已结题。
